Materia Medica

Ganodermataceae

Reishi

Ganoderma lucidum

A woody medicinal mushroom revered as a shen tonic — calming the spirit, deepening sleep and modulating immune function over the long term.

Also known as
Lingzhi, Mushroom of immortality
Parts used
Fruiting body
Taste
Bitter, Slightly sweet
Energetics
Neutral · Drying
Sourcing
Cultivated

Actions

ImmunomodulantAdaptogenCalmingHepatoprotectiveAntiallergic

Traditional use

Listed as a superior herb in the Shennong Bencao Jing (c. 200 CE) — safe for long-term use to 'lighten the body and prolong life'.

Taoist practitioners used it to calm the shen (spirit) and support meditative practice.

Research

  • Immune modulation as adjunct in cancer care

    Clinical

    A Cochrane review found reishi may enhance tumor response and immune markers alongside conventional treatment, but trials were low quality.

    Jin X et al. Cochrane Database Syst Rev. 2016;4:CD007731.

  • Improves sleep in animal models

    Preclinical

    Extracts increase non-REM sleep in rodents, possibly via TNF-α-related pathways.

Key constituents

β-glucans (polysaccharides)
Water-soluble; engage innate immune receptors such as Dectin-1.
Ganoderic acids (triterpenes)
Alcohol-soluble; bitter, antihistamine and hepatoprotective activity.

Sourcing notes

Prefer log-grown fruiting bodies over mycelium-on-grain products, which can be mostly starch.

Our sourcing standards →