Materia Medica

Passifloraceae

Passionflower

Passiflora incarnata

The herb for circular thinking: passionflower quiets mental chatter, eases anxiety and helps those who lie awake replaying the day.

Also known as
Maypop, Purple passionflower
Parts used
Aerial parts
Taste
Bitter
Energetics
Cooling · Neutral
Sourcing
Cultivated

Actions

AnxiolyticHypnoticSpasmolyticNervine relaxant

Traditional use

Used by Indigenous peoples of the southeastern United States as food and medicine. Spanish missionaries named it for the Passion of Christ, reading the crucifixion in its flower.

Adopted by the Eclectics and later European phytotherapy for insomnia, nervous restlessness and seizure-like spasms.

Research

  • Comparable to oxazepam for generalized anxiety

    Clinical

    A small pilot RCT found similar anxiety reduction to oxazepam with less impairment of job performance.

    Akhondzadeh S et al. J Clin Pharm Ther. 2001;26(5):363–367.

  • Reduces preoperative anxiety

    Clinical

    Several trials show reduced anxiety before surgery and dental procedures.

Key constituents

Flavonoids (vitexin, isovitexin, chrysin)
C-glycoside flavones; chrysin binds benzodiazepine receptors in vitro.
Harmala alkaloids (trace)
Present in very low amounts in P. incarnata.

Sourcing notes

Vigorous native vine; harvest flowering and fruiting tops in summer.

Our sourcing standards →